| abstract |
【Task】 An object of the present invention is to provide an activator of PPARδ. [Solution] The present invention relates to the following general formula (I), (Wherein R 1 is an optionally substituted phenyl group, R 2 is an alkyl group having 1 to 8 carbon atoms, A is an oxygen atom, etc., X is an alkylene chain having 1 to 8 carbon atoms, etc.) , Y is C (= O), R 3 , R 4 and R 5 are hydrogen atoms, alkyl groups having 1 to 8 carbon atoms, B is CH and the like, Z is an oxygen atom or sulfur atom, R 6 and R 7 represent a hydrogen atom, etc., and R 8 represents a hydrogen atom, etc. provided that at least one of R 3 , R 4 and R 5 is not a hydrogen atom. And a PPARδ activator containing the compound or a salt thereof as an active ingredient. [Selection figure] None |