http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009278906-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dae64c775f32c43199adbb4389c2c9b3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2008-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e814c588d7bb170de458cff7fb65063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b3f3c78c7d568604e8970c17b312f88 |
| publicationDate | 2009-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009278906-A |
| titleOfInvention | Genetically modified cultured skin and screening method for skin barrier function improving substance using the same |
| abstract | An object of the present invention is to construct a cultured cell model having damage to the stratum corneum and reflecting sensitive skin in humans, and to provide a method for screening a barrier improving substance using the model. . Epidermal cells in which expression of at least one factor gene selected from PPARα, β / δ, γ, Elovl1, 3, 4, SREBP-1c and LXRα is suppressed, collagen and fibroblasts Cultured skin containing cells; culturing fibroblasts in a collagen gel, seeding epidermal cells on which expression of the factor is suppressed, and further culturing to form a stratum corneum Method: A screening method for a barrier function improving substance, wherein the cultured skin is used for evaluating whether or not the evaluation substance improves the skin barrier function. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013541957-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018183105-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015091781-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101932248-B1 |
| priorityDate | 2008-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 904.