| abstract |
The present invention provides a quinoline derivative having a neurokinin 2 (NK2) receptor antagonistic action. Formula (I) [Wherein R 1 is a hydrogen atom; R 2 is a hydrogen atom, an optionally substituted hydrocarbon group, etc .; R 3 is unsubstituted, a hydrogen atom, etc .; R 4 and R 5 are Hydrogen atom, hydrocarbon group, etc .; R 6 is (optionally substituted cyclic group) -carbonyl etc .; R 7 , R 8 , R 9 and R 10 are the same or different and each represents hydrogen R 7 and R 8 , R 8 and R 9 , and R 9 and R 10 may form a ring with adjacent carbon atoms; n is an integer of 1 to 5; -Represents unsubstituted (ie absent) or single bond; --- represents single or double bond. Or a salt thereof. [Selection figure] None |