| abstract |
PROBLEM TO BE SOLVED: To provide a patch excellent in transdermal absorbability and storage stability of a free basic drug. SOLUTION: The patch of the present invention contains a predetermined amount of a fatty acid having an aliphatic hydrocarbon group having 8 to 22 carbon atoms in the plaster layer, so that the free base in the plaster layer Without impairing the storage stability of the active drug, the solubility and diffusibility of the free basic drug are improved to enhance the transdermal absorbability, and a sufficient amount of the free basic drug is diffused in the plaster layer. Therefore, continuous transdermal administration of a free basic drug is possible. [Selection] Figure 1 |