| abstract |
MMPs and in particular MMP2 inhibitors, MMP-dependent diseases, in particular inflammatory diseases, rheumatoid arthritis, osteoarthritis, tumors (tumor growth, metastasis, progression or wetting) and lung diseases (eg emphysema, COPD) ) Provision of compounds useful in treatment. SOLUTION: Formula (I) [Wherein R 1 is hydrogen, an aryl group or the like; R 2 is hydrogen or a lower alkyl group; R 3 is an aryl group or the like; A is an alkylene or the like; q is 1 to 5; R is an alkyl group or the like. ] The alpha-amino hydroxamic acid derivative represented by this. [Selection figure] None |