abstract |
【Task】 The present invention provides an aqueous preparation containing colloidal iron chondroitin sulfate sulfate colloid that does not contain a BSE causative substance, is safe, has excellent pharmaceutical stability, and is stable even when blended into a high-calorie parenteral nutrition infusion. Is an issue. [Solution] The present invention adds a ferric chloride aqueous solution and a sodium hydroxide aqueous solution to a koji-derived chondroitin sulfate aqueous solution to obtain a koji-derived chondroitin iron sulfate colloid, and after heating, a pH buffer is added, and then a trace element is added. The present invention relates to an aqueous preparation characterized by adding sodium hydroxide after adding one or more of selenium, zinc, copper, iodine and manganese. [Selection figure] None |