| abstract |
Disclosed is a novel therapeutic agent for diseases and alterations mediated by asymmetric and pathological neuronal exocytosis. A novel peptide having a sequence of 3-30 contiguous amino acids from the amino terminus of protein SNAP-25 and useful as a neuronal exocytosis inhibitor is used. The pharmaceutical composition of the invention comprises the peptide and optionally one or more peptides from the carboxyl terminus of SNAP-25. [Selection figure] None |