http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009209106-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e61866e714198ee02a24037c9670828 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
filingDate | 2008-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36c90ce106f5a080653aad4f6afe6a76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec6154380bc955fd3ed78776e7e3bb86 |
publicationDate | 2009-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2009209106-A |
titleOfInvention | Process for producing 2-imino-4-thiazolidinone derivatives and 2,4-thiazolidinedione derivatives |
abstract | An object of the present invention is to reduce 5- [4- [2- {N-methyl-N- (2-pyridyl) amino} ethoxy] benzyl] -2,4-thiazolidinedione (generic name: rosiglitazone) with fewer steps, And the manufacturing method which can be obtained with a high yield is provided. 4- [2- {N-methyl-N- (2-pyridyl) amino} ethoxy] benzaldehyde and 2-imino-4-thiazolidinone are subjected to a condensation reaction to give a novel compound 5- [4- [ 2- {N-methyl-N- (2-pyridyl) amino} ethoxy] benzylidene] -2-imino-4-thiazolidinone was obtained and the novel compound was reduced to give 5- [4- [2- {N- Methyl-N- (2-pyridyl) amino} ethoxy] benzyl] -2-imino-4-thiazolidinone, which is hydrolyzed to give 5- [4- [2- {N-methyl-N- (2 -Pyridyl) amino} ethoxy] benzyl] -2,4-thiazolidinedione. [Selection figure] None |
priorityDate | 2008-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.