abstract |
The present invention provides humanized antibodies (eg, antibodies that bind to ICAM-1), methods of use and methods of generating antibodies. The antibody of the present invention comprises a sequence having a VH domain and a VL domain selected from HumA, HumB, HumC, HumD, HumE, HumF, HumG, HumH, HumI, Hum40 and Hum50. Partial sequences of antibodies that bind ICAM-I (eg, single chain fragments, Fab fragments, Fab ′ fragments, and (Fab) 2 fragments) are provided. As described above, the above problems have been solved. [Selection figure] None |