abstract |
PROBLEM TO BE SOLVED: To provide a protonated compound having antibacterial activity. The present invention further provides antimicrobial compositions comprising the protonated compounds of the present invention. The protonated compounds of the present invention provide effective antimicrobial activity against resistant strains of bacteria and opportunistic fungi. (A) a protonated compound, wherein the compound has the structure: XYZ Wherein X and Z are end-blocking agents and Y is phosphorus containing a moiety containing one or more protonation sites, and the compound is introduced into a reactive site on the molecule A compound comprising one or more exogenous protons, and (b) an excipient. [Selection figure] None |