| abstract |
A highly marketable artery that simplifies the skeletal structure while preserving the spatial structure of substituents induced by the natural skeleton of Beauveriolide, improves its chemical synthesis efficiency, and improves water solubility and pharmacokinetics. Providing preventive and therapeutic drugs for sclerosis. A cyclic compound having the formula (1). [In the formula (1), Y is CH 2 , CH 2 —CH 2 or CH═CH, n is 0 or 1, R 1, R 3 and R 4 are alkyl groups, alkenyl groups, alkynyl groups, aryls A group, an aralkyl group (which may have a hetero atom in the group and may be substituted with a substituent), an amino group (only R 4 ), or R 2 is an aryl having at least one aromatic ring A group or an aralkyl group (which may have a heteroatom in the group or may be substituted with a substituent); ] [Selection figure] None |