| abstract |
PROBLEM TO BE SOLVED: To provide a filter having a function of removing abnormal prions from biological fluids such as blood products, and to provide a filter capable of removing white blood cells simultaneously with abnormal prions. A filter for selectively reducing a target substance in a biological fluid, comprising a carrier stacked in a container having a fluid outlet and an inlet, the layered carrier being at least the following: A filter having a prion removal function, characterized by comprising the configurations of A and B. A: It has a modified cross-section fiber nonwoven fabric. B: 20 mol% or more and 40 mol% or less of a hydrophobic polymerizable monomer-derived unit, 5 mol% or more and 13 mol% or less of a polymerizable monomer-containing unit containing a basic nitrogen-containing moiety, and the balance is a protonic neutral hydrophilic And a carrier coated with a polymer composed of three units, which are units derived from a polymerizable monomer containing a functional moiety. [Selection figure] None |