abstract |
Disclosed is a compound exhibiting high action specificity and low toxicity as compared with known compounds having a similar structure and improved blood stability. A linker arm is provided that liberates an active drug moiety from a prodrug derivative that is cleaved enzymatically or reductively in vivo to include a linker arm. The linker arm further includes conjugates between cytotoxins and linker arms, conjugates between cytotoxins and targeting agents such as antibodies or peptides. [Selection figure] None |