| abstract |
An object of the present invention is to provide a safe immunostimulant that can be used as a pharmaceutical or food material and a method for producing the same. Moreover, the novel utilization method of a coffee extraction residue is also provided. The present invention provides an immunostimulant comprising a coffee extract as an active ingredient. Preferably, the coffee extract is an immunostimulant that is an extract containing arabinogalactan. Moreover, this immunostimulatory activity is derived from the promotion of proliferation of immunocompetent cells such as macrophages. Here, it is preferable that the immunocompetent cell is any one of a macrophage-like cell line RAW264, a mouse spleen cell, and a mouse peritoneal macrophage. Moreover, the composition containing these immunostimulants can be utilized as a composition of a pharmaceutical composition, a food composition, or a cosmetic composition. [Selection] Figure 1 |