abstract |
A novel pharmaceutical composition having high bioavailability due to improved solubility and a method for preparing the same are provided. The invention relates to rotation at 75 rpm according to the European Pharmacopoeia in a dissolution medium comprising fenofibrate and composed of water containing 2% by weight of polysorbate 80 or 0.025 M sodium lauryl sulphate. Immediate release with a resolution of at least 10% at 5 minutes, at least 20% at 10 minutes, at least 50% at 20 minutes, and at least 75% at 30 minutes as measured using the blade method release) relates to the composition. [Selection figure] None |