abstract |
The present invention provides a novel compound having an excellent inhibitory action against dipeptidyl peptidase IV (DPPIV), a method for producing the same, use thereof, and the like. A 2-cyanopyrrolidine derivative represented by the following general formula [I] or a pharmacologically acceptable salt thereof, a production method thereof, a pharmaceutical composition containing the compound as an active ingredient, and an activity of DPPIV It relates to the use etc. of said compounds for inhibiting. [Wherein R represents (1) morpholino or (2) optionally substituted piperazin-1-yl. ] [Selection figure] None |