| abstract |
Disclosed is a compound having a neurite outgrowth-inducing action and a neuroprotective action. The inventors of the present invention have the formula (I) including KNK437. [Chemical 1] (In the formula, X represents βCH 2 β and R 1 represents an alkyl group having 1 or 2 carbon atoms, a formyl group, an acetyl group, a hydrogen atom or a halogen atom, or X represents β (CH 2 ) 2. And R 1 represents an alkyl group having 1 to 3 carbon atoms, a formyl group, an acetyl group, a hydrogen atom or a halogen atom), and has a neurite outgrowth-inducing action and a neuroprotective action, It was found for the first time that a synergistic effect was exhibited in combination with nerve growth factor, and the present invention was completed. [Selection figure] None |