| abstract |
Provided is a method for producing an asymmetric catalytic aldol reaction product capable of obtaining an aldol form with high asymmetric yield by using acetaldehyde as a nucleophile in an asymmetric catalytic aldol reaction between aldehyde and aldehyde. . An asymmetric catalyst represented by the following general formula (2) or an enantiomer thereof is used as an asymmetric catalyst in an asymmetric catalytic aldol reaction. [Wherein R 2 and R 3 are each independently an aryl group, heteroaryl group, cycloalkyl group, heterocycloalkyl group, cycloalkenyl group, heterocycloalkenyl group, alkyl group which may have a substituent. , An alkenyl group, or an alkynyl group, R 4 represents a hydrogen atom, a silyl group, or an alkyl group, R 5 represents a hydroxyl-protecting group, and n represents 0 or 1. ] [Selection figure] None |