abstract |
A method for determining a new mental illness based on biological characteristics and a method for searching for a new substance capable of preventing or treating the mental illness are provided. [MEANS FOR SOLVING PROBLEMS] By means of hierarchical clustering, a cluster in which psychiatric patients having gene expression patterns similar to CaMKIIα heterodeficiency, which is a model animal of schizophrenia, accumulate is identified, and psychiatric patients included in this cluster are identified. By comparing the gene expression profile with non-psychiatric patients, a gene whose expression level varies in mental illness was newly found. The present invention provides a method for determining a mental illness using the gene and a method for searching for a substance capable of preventing or treating the mental illness. [Selection figure] None |