abstract |
Disclosed are sulfonated diarylrhodamine compounds that are useful as fluorescent labels for nucleosides, nucleotides, polynucleotides, and polypeptides. The compounds of the present invention find particular use in fields such as fluorescent nucleic acid analysis (eg, automated DNA sequencing) and fragment analysis, detection of probe hybridization in hybridization arrays, detection of nucleic acid amplification products, etc. Yes. Another aspect of the present invention includes an energy transfer dye compound that absorbs light at a first wavelength and is capable of emitting excitation energy in response; emitted by the donor dye; An acceptor dye that can absorb the excited excitation energy and fluoresce at a second wavelength in response; and a linker for linking the donor dye and the acceptor dye. [Selection figure] None |