http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009102445-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c4ceeea48f9a6c3a30a1250206b73e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_995c71109762882f3cc26e74d8d61acf |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10 |
| filingDate | 2009-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2d67442f48e0321a00019f875c8a4a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01a334ca8ba501ad3d69ce1fab83553f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b00d81711bec9ce61177ef46b5b6ef59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db6b012180a73b83d59160df59eab733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd5c0dd88d55a2977f928b60adb15ce |
| publicationDate | 2009-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009102445-A |
| titleOfInvention | Semi-synthetic rearranged vancomycin / desmethyl-vancomycin-based glycopeptide with antibacterial activity |
| abstract | PROBLEM TO BE SOLVED: To have improved antibacterial activity, possibility of less resistance, improved efficacy against bacterial infections resistant to currently available antibiotic treatments, or unexpected selectivity for targeted microorganisms New derivative compounds are identified. Semi-synthetic glycopeptides having antibacterial activity modify translocated vancomycin or desmethyl-vancomycin backbones, in particular the alkylation or acylation of amino substituents of amino-substituted sugar moieties in this backbone with certain acyl groups; And / or based on conversion of the acid moiety in the macrocyclic ring of the backbone to certain substituted amides. Also provided herein are methods of synthesizing the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat and / or prevent diseases, particularly bacterial infections. [Selection figure] None |
| priorityDate | 2005-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.