| abstract |
The present invention provides a nucleoside compound that produces a cytotoxic purine upon enzymatic cleavage. The following formula: [Chemical 1] Wherein A is a cytotoxic purine; R 1 and R 2 are each independently a substituted hydryl group, C 1 -C 6 alkyl group, C 6 -C 10 aryl group, C 0 -C 6 R 3 and R 4 are each independently a hydryl group, a C 1 -C 6 alkyl group, a C 6 -C 10 aryl group, a C 2 -C 6 alkenyl group, a C 2 -C 6 An alkynyl group, a heteroatom-substituted C 1 -C 6 alkyl group or a C 6 -C 10 aryl group). [Selection figure] None |