| abstract |
[PROBLEMS] To provide an advantage of a water-soluble matrix and not only to operate a separate controlled release system in the stomach and intestine, but also to maintain a constant matrix form of the niacin formulation until the elution of the niacin formulation is completed. Provided are a novel niacin-controlled release formulation and a method for producing the same, in which drug release is controlled very precisely. Niacin, hydroxypropylmethylcellulose, and carboxyvinyl polymer are included, wherein carboxyvinyl polymer and hydroxypropylmethylcellulose are included such that carboxyvinyl polymer: hydroxypropylmethylcellulose has a specific weight ratio. Niacin controlled release formulation. [Selection] Figure 3 |