abstract |
A transdermal system comprising a neutralized acrylic adhesive patch that improves the water absorption of a pressure-sensitive adhesive polymer containing acrylic acid or methacrylic acid in its polymer chain and improves its overall moisture resistance. Provision of treatment system. A transdermal therapeutic system embodied as a matrix system or reservoir system. The transdermal therapeutic system comprises at least one pharmaceutical agent acting as basic or neutral, and a contact adhesive polymer having acrylic acid or methacrylic acid units as part of the polymer chain, and having a carboxyl group The content of is 0.5 to 10.0% (w / w) of the polymer material, and the carboxyl group is 5 to 100%, preferably 10 to 10% in the form of an alkali salt or an alkaline earth salt. Present at 50% stoichiometry. In order to reduce moisture sensitivity, a water-binding additive may be included. [Selection figure] None |