abstract |
Disclosed is a plasminogen activator inhibitor-1 (PAI-1) inhibitor and a novel compound which is an active ingredient thereof. The present invention also provides a pharmaceutical composition that has an action of inhibiting PAI-1 activity and is effective in preventing or treating various diseases in which PAI-1 activity is involved in the onset. The PAI-1 inhibitor and pharmaceutical composition of the present invention comprise a novel compound having a PAI-1 inhibitory activity represented by the following general formula (I) and a salt thereof as active ingredients. [Chemical 1] [Selection figure] None |