http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009029794-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9999d359590090d93af9785ab9501e0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate | 2008-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_639174159420c0e506a6df0cd838ad48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1896bbed2a454924b20fa5c02b9e8d3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_100dae9ef56404be344bb69fe317b81e |
| publicationDate | 2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009029794-A |
| titleOfInvention | Method for producing caged compound |
| abstract | A conventional caged compound production method is a so-called tri-and-error method in which synthesis and evaluation are repeated in order to predict functional groups important for activity. Peptides and proteins that can be caged to control physiological activity due to the problems that it is difficult to provide a stable and inexpensive product and side chain functional groups (alanine, leucine, etc.) that cannot be modified with a photolabile protecting group Has a problem that it is limited. [MEANS FOR SOLVING PROBLEMS] A biopolymer compound having biological activity has one group of a selective chemically synthesized group and a photocleavable amino acid at one of the N-terminal and C-terminal of a biopolymer having biological activity, and selective chemistry at the other terminal. By synthesizing the other group of the synthetic group pair and carrying out an intramolecular cyclic reaction by intramolecular selective chemical reaction, the conjugate of the biopolymer compound and the photocleavable amino acid is cyclized to produce a biologically active bioactive compound. This is a method for producing a caged compound in which the activity of a molecule is inhibited. [Selection] Figure 2 |
| priorityDate | 2007-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.