| abstract |
Provided is a further replication-defective adenoviral vector capable of introducing and expressing a foreign nucleic acid and having an infectious physiological function different from that of a group C adenoviral vector. An adenovirus isolated from an adenovirus classified into group A, B, D, E or F, or containing an adenovirus DNA segment substantially homologous to the DNA segment contained in adenovirus, and virus replication Adenoviral gene transfer vector deficient in at least one of the necessary regions for the use, and a method of using the vector. [Selection] Figure 1 |