| abstract |
Disclosed is a sustained-release preparation of a tricyclo compound characterized in that elution of a tricyclo compound (macrolide compound) such as tacrolimus, rapamycin, and ascomycin is sustained-released. A sustained-release preparation comprising, as a component, a solid dispersion in which a tricyclo compound is present in an amorphous state in a solid base or a fine powder of a tricyclo compound. The solid base is selected from methacrylic acid copolymers, sucrose fatty acid esters, and hydroxypropyl methylcellulose. [Selection figure] None |