| abstract |
The present invention provides pharmaceutical formulations comprising antibodies or antigen-binding fragments thereof that exhibit high stability, together with methods of use thereof. The pharmaceutical formulations of the invention comprise an isolated antibody or antigen-binding fragment thereof that specifically binds to IGF1R, a buffer and sucrose. The kit of the invention comprises (a) a formulation of the invention in a container or infusion device; and (b) pharmacokinetics, pharmacodynamics, clinical studies, efficacy parameters, indications and usage, contraindications, warnings, precautions, harmful One or more information items related to the formulation selected from the group consisting of reaction, overdose, appropriate dose and administration, how to be supplied, appropriate storage conditions, references and patent information Including a package insert. |