| abstract |
Provided is a compound having the formula I, wherein R 1 -R 5 , A, G, L and X have the meanings given herein, the compound comprising a trypsin-like protease such as thrombin Are useful as competitive inhibitors of, or are useful as their prodrugs, and in particular, in situations where inhibition of thrombin is beneficial (eg, thrombin inhibition is required, such as thromboembolism) Useful or desired conditions, and / or conditions where anticoagulant therapy is required). |