| abstract |
Compounds that regulate GHS-R are described, for example compounds of formula (I). The invention further relates to compositions comprising these compounds, and methods of using and making the compounds. Some examples of compounds include sulfonamide compounds (eg, heteroaryl sulfonamide compounds), and other sulfonamide compounds having a cyclic moiety. Examples of heteroaryl compounds include oxadiazole compounds and triazole compounds. This compound can be used in therapeutic applications to modulate a disorder, disease or condition in a subject (eg, mammal, human, dog, cat, horse). This compound includes useful GHS-R antagonists. This antagonist can be used, for example, to reduce a subject's food intake. |