abstract |
The present invention relates to a penicillin-binding protein expressed by Neisseria meningitidis, or a fragment, mutant, or mutant fragment thereof, or a nucleic acid encoding them, or an antibody against them, as a pharmaceutical or pharmaceutical composition It relates to antibody fragments. The present invention also provides a prophylactic and / or therapeutic treatment for mammals, preferably humans, against infection with N. meningitidis and / or infection with bacterial strains expressing mutants of N. meningitidis penicillin binding protein. It also relates to the use of penicillin binding proteins expressed by Neisseria meningitidis, or nucleic acids encoding them, or antibodies against them for the purpose of immunotherapy. |