| abstract |
The present invention is directed to methods for preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating a thrombus or related disease. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, said amount being effective to inhibit platelet aggregation. Compounds useful in the present invention include compounds of general formulas I and III-XII, their salts, hydrates and solvates. The present invention also provides novel compounds of formulas I and III-XII. |