| abstract |
[Chemical 1] The present invention contains cyclic amine side chains having binding affinity for serotonin receptors, particularly 5-HT 2A and 5-HT 2C receptors, and for dopamine receptors, particularly dopamine D 2 receptors. Novel tetracyclic tetrahydrofuran derivatives, pharmaceutical compositions comprising the compounds according to the invention, as drugs, in particular a range of psychiatric and neurological disorders, in particular certain psychotic, cardiovascular and gastric The present invention relates to their use as medicaments for the prevention and / or treatment of motility disorders and to methods for their production. The compounds according to the invention can be represented by the general formula (I), which are pharmaceutically acceptable acid or base addition salts, their stereochemical isomers, their N-oxide forms and their quaternary ammonium salts. Wherein all substituents are defined as in claim 1. |