http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008540553-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2006-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008540553-A |
| titleOfInvention | Method for modulating HLA class II tumor cell surface expression by cytokine mixtures |
| abstract | Modulating expression of HLA (human leukocyte antigen) class II on the surface of tumor cells. IL-1β for IL-2, TNF-α for IL-2, IFN-γ for IL-2 Serum-free with a specific cytokine ratio from the group of IL-1β, TNF-α, IFN-γ, GM-CSF and interleukin-2 (IL-2) with a specific ratio of GM-CSF to IL-2 And mitogen-free mixtures alter the composition of tumor-infiltrating mononuclear cells, increase the CD4 + / CD8 + ratio, increase the tumor stroma / epithelium ratio, and express HLA (human leukocyte antigen) class II on the tumor cell surface It is a method for modulating. Serum-free and mitogen-free mixtures with specific cytokine ratios can be further used with or in combination with other medicines for cancer treatment, increasing cancer treatment success rate and disease-free survival of cancer patients Which can include leukocyte interleukins, injections or Multikine®. [Selection] Figure 3 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010054305-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018514558-A |
| priorityDate | 2005-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 408.