abstract |
The present invention provides a bakuchiol composition (UP246) with a low concentration of impurities, particularly furanocoumarin impurities. The present invention further provides an improved method for separating, purifying and analyzing bakuchiol compositions. Furthermore, the present invention provides a purified bakuchiol composition and formulations thereof for the prevention or prevention of various diseases and conditions mediated by cyclooxygenase (COX), lipoxygenase (LOX), mild inflammatory conditions, and various microbial infections. Provide a method for use in therapy. The method of the invention comprises administering to a host in need thereof an effective amount of the composition of the invention together with a pharmaceutically acceptable carrier. [Selection figure] None |