| abstract |
Provided herein are drugs, compositions, and grafts for the treatment of diverticular disease (eg, diverticulosis and diverticulitis). In particular, compositions containing fibrogenesis-inducing agents, hemostatic agents, and / or anti-infective agents, or one or more of these agents for use in the treatment of diverticular disease are provided. In certain embodiments, it induces adhesions or fibrosis to the diverticulum wall, or promotes "filling" of the diverticulum in situ, removing the lumen of the diverticulum and relieving symptoms or Implants (or biomaterials) soaked with therapeutic agents or drugs that reduce the risk of developing are provided. In various embodiments, fibrosis is induced in the diverticulum by local (intraluminal) or local release of certain pharmacological agents delivered to the site by endoscopy or catheter-based procedures. The |