abstract |
The present invention relates to methods and compositions for the generation and derivation of pluripotent stem cells from embryos or embryo-derived cells and therapeutic uses related thereto. In particular, the present invention is a method for producing a functional stem cell or stem cell-like cell, comprising culturing an embryo or embryo-derived cell in the presence of a demethylating agent, and a functional pluripotent cell. And a method comprising the step of isolating. |