| abstract |
The present invention provides a method for measuring a cellular response to a stimulus. The cells to be tested can be contained in a section of the tongue epithelium including, for example, taste buds. The present invention provides a method for determining a functional cellular response to one or more stimuli of taste cells (ie, taste sensory cells in intact epithelial tissue containing taste buds) contained in a slice of tongue epithelium containing taste buds. . In the present invention, a tissue, such as an animal-derived taste tissue (eg, epithelial tissue containing taste buds or taste papillae) is contacted with one or more stimuli, and the magnitude of at least one cell signaling event triggered by the stimulus is quantified. Measure automatically. |