abstract |
The present invention relates to methods and compositions for treating and reducing symptoms and diseases associated with indications caused by physiological motives to alleviate the sense of anxiety. More particularly, the present invention relates to methods and compositions for treating and reducing symptoms associated with substance abuse and withdrawal. The present invention relates to methods and compositions for treating and reducing symptoms associated with addiction of antidepressants, opiates, nicotine or marijuana. In one method, a patient is treated with a composition that modulates the GABA A directly or indirectly by modulating the expression of GABA A receptor a 4 subunit. |