| abstract |
The present invention selectively selects signal transduction mediated by certain native and / or mutant tyrosine kinases associated with various human and animal diseases such as cell proliferative diseases, metabolic diseases, allergic diseases and degenerative diseases. It relates to novel compounds selected from substituted oxazole derivatives of formula (I) which modulate, control and / or inhibit. More particularly, these compounds are potent and selective c-kit, bcr-abI and Flt-3 inhibitors. |