abstract |
The present invention provides a series of substituted bicyclic [3.1.0] heteroarylamides of Formula I (A, Q, X, Y, Z and R 1 -R 5 groups that exhibit activity as glycine transport inhibitors. As defined in the specification), pharmaceutically acceptable salts thereof, pharmaceutical compositions containing it, and increased awareness in mammals, including humans, to treat positive and negative symptoms of schizophrenia and other psychosis Related to its use to do. |