| abstract |
The present invention provides a compound of formula I, wherein R 1 , R 3 , X, W, Z and ring Y are as defined herein. The present invention also provides compositions comprising these compounds that are useful for treating cell proliferative diseases or disorders associated with KSP kinesin activity and for inhibiting KSP kinesin activity. A method of treating a cell proliferative disease, disorder associated with KSP kinesin activity and / or inhibiting KSP kinesin activity in a subject, wherein a subject in need of such treatment is treated with at least a compound of the invention. Also provided is a method comprising administering one effective amount. |