| abstract |
The present invention provides (a) Formula I: I Wherein M represents a macrolide subunit (macrolide moiety) derived from a macrolide that has the property of accumulating in inflammatory cells, and D is a dibenzo [e , H] represents an azulene subunit, and L is a linking group that covalently bonds M and D) (B) pharmaceutically acceptable salts, prodrugs and solvates thereof, (c) methods and intermediates for their preparation, and (d) inflammatory diseases in humans and animals and Relates to its use in the treatment of conditions. |