http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008532519-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 2006-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2008532519-A |
titleOfInvention | Methods and compositions for in vivo imaging of gene expression |
abstract | A nucleic acid sequence operably linked to a sequence of a tissue selective promoter is disclosed that encodes the amino acid sequence of a recombinant seven-transmembrane G protein coupled receptor (GPCR). In addition, a nucleic acid that is operably linked to a tissue selective promoter or an amplified tissue specific promoter and that encodes a reporter that is detectable using a non-invasive method is introduced into the subject. Also disclosed are methods of imaging or treating a cell in a subject comprising the steps and subjecting the subject to a non-invasive imaging technique or therapeutic agent that selectively interacts with a reporter or gene of interest. For example, the subject can be a subject with cancer and the therapeutic agent can be an anti-cancer agent. In particular, the hTERT promoter or amplified hTERT promoter drives the expression of reporters such as hSSTR2 and / or hSSTR2 derivatives. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016101161-A |
priorityDate | 2005-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 2304.