| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-626
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2005-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2008-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008531557-A |
| titleOfInvention |
Bispecific binding agents for modulating biological activity |
| abstract |
A method for enhancing the specific binding ability of a bispecific binding composition is described. A bispecific binding composition can target cells with a high affinity target domain for a target cell surface marker and a low affinity binding domain that specifically binds to a second cell surface marker, wherein The binding of each domain to the respective cell surface marker increases or decreases the biological activity of the respective cell surface marker as desired. The present invention further provides bispecific binding agents and uses of these agents for use in the present methods. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012521196-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11773170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780925-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014500024-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016538242-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017512756-A |
| priorityDate |
2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |