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filingDate 2006-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2008-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2008531032-A
titleOfInvention Transgenic mice and their use as experimental models
abstract The present invention relates to the use of an expression vector encoding a functional complex specifically recognized by an anti-HLA-DP antibody for producing a transgenic mouse, said mouse, and induced after viral infection. Use of the mouse as an experimental model for studying an immune response or an immune response induced by a test compound. The invention relates to the use of an expression vector construct encoding a functional HLA-DPα103β401 complex specifically recognized by an anti-HLA-DP antibody to generate a transgenic mouse, said construct comprising DPα103 and DPβ401. A mouse promoter for the IAβ gene and IAα gene related to the cDNA encoding [Selection figure] None
priorityDate 2005-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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