abstract |
A drug delivery device is described that includes an occlusive backing layer and a drug depot comprising a TR-JPV1 agonist and a non-hydrophilic solvent. The drug depot can take various forms, such as an adhesive polymer matrix, a liquid reservoir, or a microreservoir droplet. A method of making and using a drug delivery device is also described. Drug depots typically include capsaicin, but can also be formulated to incorporate other TRPV1 agonists such as capsaicinoids, capsaicin analogs, and capsaicin derivatives. |