| abstract |
The present invention represents a compound of formula I (wherein W represents a COOH group or a biological equivalent thereof, or —COO—C 1 -C 4 -alkyl group; Y represents NH, N—C 1 -C 10; - alkyl, represents O or S; Z is, NH, N-C 1 -C 10 - alkyl, N- aryl, N- heteroaryl, S or O; X is, O, S, NH, N- C 1 -C 10 -alkyl, N-aryl, NSO 2 -C 1 -C 10 -alkyl, N—SO 2 -aryl or N—SO 2 -heteroaryl is shown; R 1 to R 6 are each independently A hydrogen atom or a substituent defined in the specification; A is as defined in the specification; and n is a comprehensive integer of 0 to 4). New compounds and their pharmaceutically acceptable salts That. The compound is a ligand of the PPAR-gamma receptor and is useful as a medicine. |