http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008526864-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 |
filingDate | 2006-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2008526864-A |
titleOfInvention | Sugar linkage using sugar fragments |
abstract | The present invention provides a conjugate between a substrate, such as a peptide, glycopeptide, lipid, etc., and a modified sugar fragment carrying a modifying group such as a water soluble polymer, therapeutic moiety or biomolecule. The conjugate is bound via enzymatic conversion of the activated modified sugar fragment to a glycosyl linking group that is interposed between and covalently bound to the substrate and the modifying group. The conjugate is formed from the substrate by the action of a glycosyltransferase, such as a glycosyltransferase. For example, when the substrate is a peptide, the enzyme attaches a modified sugar fragment moiety to an amino acid residue or glycosyl residue of the peptide. Pharmaceutical formulations comprising the conjugate are also provided. Methods for preparing the conjugate are also within the scope of the present invention. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975346-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2013042581-A1 |
priorityDate | 2005-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1124.